Cell Based Assays
Eurofins Discoverx PathHunter eXpress ACVRL1/ACVR2 Dimerization Assay, 10pl Kit. (93-0963E3CP0L)
The PathHunter ACVRL1/ACVR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. GDF2/BMP9) induced dimerization of ACVRL1/ACVR2 receptors. This product uses EFC technology. The cell line included overexpresses ACVR2 target protein fused to PK alongside ACVRL1 target protein fused to EA. Upon ligand-induced dimerization of ACVRL1/ACVR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HEK 293 RELA Nuclear Translocation Assay, 2-plate Kit. (93-0907E1CP0M)
The PathHunter eXpress HEK 293 RELA Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the NFκB pathway. This assay kit enables assessment of ligand (e.g. IL-1α) based pathway activation via detection of resulting RELA nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLink-tagged RELA and nuclear localized EA. Upon pathway activation, induced nuclear translocation of RELA leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Apexbio Technology LLC Caspase-4-Colori-Assay-Kit
Caspase-4 Colorimetric Assay Kit is designed for apoptosis research This colorimetric assay originates from studies focused on the role of caspases which are crucial in programmed cell death pathways Caspase-4 specifically targets inflammatory responses within the endoplasmic reticulum stress pathway The kit enables detection of enzymatic activity within the nanomolar to low micromolar range allowing researchers to quantify caspase activation with precision It is commonly applied in vitro using various cell models including human cell lines and is also utilized in animal studies for investigating inflammation-related diseases Additionally it serves as a valuable tool in drug screening to evaluate potential inhibitors or activators of caspase-4 Experimental concentrations typically depend on the specific research design allowing flexibility for diverse scientific investigations
Revvity Health Sciences Inc LANCE Ultra Total STAT3 Detection Kit, 10,000 Assay Points
LANCE Ultra Total STAT3 Detection Kit, 10,000 Assay Points
Sartorius iQue Membrane Integrity Kit
Three dye options gives you more ways to measure cell death.No wash protocol just add and read for fast easily automated workflow.Multiplex with other IntelliCyt kits like Cell Cycle for richer content.PrincipleThe Cell Membrane Integrity dyes are fluorescent molecules that are cell impermeant. Healthy cells with intact cell membranes will exclude the dyes. Unhealthy cells with compromised membranes will allow entry of the dye into the intracellular space. Upon entry to the cell the dye localizes to the nucleus and binds to DNA by intercalation.
Revvity Health Sciences Inc HTRF Human Total FGFR2 Detection Kit, 500 Assay Points
HTRF Human Total FGFR2 Detection Kit, 500 Assay Points
BPS Bioscience Inc SARM1 Fluorogenic Assay Kit (Hydrolase Activity) 384 reactions
The SARM1 Fluorogenic Assay Kit (Hydrolase Activity) is designed to measure NAD+ cleavage activity in screening and profiling applications. The SARM1 assay kit comes in a convenient 96 or 384-well format, with enough recombinant human SARM1 enzyme (amino acids 28-724), its substrate N6-etheno-NAD (e-NAD), and SARM1 assay buffer for 100 or 400 enzyme reactions. In addition, the kit includes a SARM1 inhibitor (DSRM-3716) for use as a control inhibitor.
Revvity Health Sciences Inc HTRF Phospho-IR-β (Insulin Receptor Beta) (Tyr1150 /1151) Detection Kit, 50,000 Assay Points
HTRF Phospho-IR-β (Insulin Receptor Beta) (Tyr1150 /1151) Detection Kit, 50,000 Assay Points
Perkin Elmer US LLC Quest ATR Accessory Ge Top Plate
The Quest ATR Accessory is a performance single-reflection ATR accessory designed for sample analysis in the mid- and far-infrared. This accessory has reflective gold-coated optics and Specac's Synopti-Focal Array technology with precision-molded aspheric mirrors. The Quest ATR Accessory is compatible with Spectrum 3/Frontier spectrometers.
Revvity Health Sciences Inc HTRF Human Phospho-p53 (Ser15) Detection Kit, 500 Assay Points
HTRF Human Phospho-p53 (Ser15) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-α-Synuclein (Ser129) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-α-Synuclein (Ser129) Detection Kit, 50,000 Assay Points
Enzo Life Sciences Cell Counting Kit-F (500 tests)
Fluorometric kit for simple and accurate cell proliferation and cytotoxicity assays. Advantages: No radioisotopes, more sensitive than the colorimetric assay, short staining reaction time, no solubilization step, correlates with the [3H]-thymidine incorporation assay. Alternative name: CCKi-F. Applications: Fluorescence microscopy .